Cell Culture Media, Supplements, and Reagents
Apexbio Technology LLC Benzydamine HCl 132-69-4 100mg
Benzydamine hydrochloride (132-69-4) is a small-molecule inhibitor targeting cyclooxygenase (COX) enzymes It is designed to inhibit COX activity thereby reducing prostaglandin synthesis and regulating inflammatory pathways Benzydamine hydrochloride exerts its biological activity primarily through COX enzyme modulation and sodium channel blockade In cell-based assays benzydamine hydrochloride demonstrates prostaglandin production inhibition with an IC50 ranging from approximately 10 to 50 M depending on the experimental model Based on these pharmacological properties benzydamine hydrochloride holds research potential in investigating inflammatory pathways analgesic mechanisms and local anesthetic activity in vitro and in animal models
Apexbio Technology LLC Doramectin,5g CAS# 117704-25-3
Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle. Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC Zaltoprofen 74711-43-6 10mg
Zaltoprofen (CAS 74711-43-6) is a nonsteroidal anti-inflammatory small molecule that functions as a cyclooxygenase (COX) inhibitor with a moderate selectivity for COX-2 over COX-1 (IC50 values of 0 34 M for COX-2 and 1 3 M for COX-1) In addition to inhibiting prostaglandin synthesis through COX modulation zaltoprofen has been shown to suppress bradykinin-induced nociceptive responses independent of its COX-inhibitory activity This multifaceted mechanism makes zaltoprofen a relevant tool for investigating inflammatory pathways and pain signaling in biomedical research
Apexbio Technology LLC Perphenazine 58-39-9 1g
Perphenazine (CAS 58-39-9) is a phenothiazine derivative that primarily acts as an antagonist at dopamine D receptors with dissociation constant (Ki) of 1 4 nM and also displays significant binding to histamine H (Ki 8 nM) A-adrenergic (Ki 10 nM) A- B- C-adrenergic and muscarinic M (Ki 1848 nM) receptors Its antagonism at D receptors underlies its ability to modulate dopaminergic neurotransmission while interaction with additional receptor subtypes may account for its effects on the central nervous system and antiemetic properties Perphenazine is widely utilized in research investigating mechanisms of antipsychotic activity dopaminergic regulation and drug-induced cell death pathways
Apexbio Technology LLC Amoxicillin trihydrate 61336-70-7 1g
Amoxicillin trihydrate (CAS 61336-70-7) is a small-molecule inhibitor targeting bacterial cell wall synthesis It is designed to inhibit peptidoglycan cross-linking thereby disrupting bacterial cell wall biosynthesis and resulting in cell lysis Amoxicillin trihydrate exerts its biological activity primarily through inhibition of bacterial transpeptidase enzymes involved in cell wall synthesis In in vitro studies Amoxicillin trihydrate demonstrates bactericidal activity with reported minimum inhibitory concentration (MIC) values of approximately 0 01 g/ml for Streptococcus viridans 0 25 g/ml for Bacillus anthracis and 50 g/ml for Retterella indica Based on these pharmacological properties Amoxicillin trihydrate holds research potential in antibacterial susceptibility testing microbial growth inhibition studies and in vitro pharmacological investigations
Apexbio Technology LLC Palifosfamide,5mg CAS# 31645-39-3
Palifosfamide is the active moiety of ifosfamide (IFA) [1].IFA is alkylating agents which are active against a variety of pediatric sarcomas such as rhabdomyosarcoma (RMS), Ewing’s sarcoma (ES), osteosarcoma (OS) and other undifferentiated soft tissue sarcomas [1].In human OS cell lines SaOS-2, OS229 and OS230, Palifosfamide lysine has broad activity with IC50 ranging from 2.25 to 6.75 μM. While OS222 had the IC50 of 31.5 μM [1].In CB17 female SCID mice, palifosfamide lysine (100 mg/kg) administered intravenously for three consecutive days, the mean weight loss was less than 15% and complete recovery to baseline within 4 weeks of treatment. Other sizes are also available. Please inqury us for quote.
Amsbio LLC MAPTrix HyGel™-E, Cadherin Hydrogel Kit, ADTPPV
MAPTrix HyGel™-E, Cadherin Hydrogel Kit, ADTPPV
Selleck Chemical LLC Nitroxoline 100mg 4008-48-4 8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline
Nitroxoline (8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. Nitroxoline impairs tumor progression in vitro and in vivo by inhibiting cathepsin B activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
eMolecules SCOPINE HCL | 85700-55-6 | MFCD00058097 | 1g
AstaTech | SCOPINE HCL | 1g | 268495432 | 42087 | 97.000 | 85700-55-6 | MFCD00058097 | 191.660 | C8H14ClNO2
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Supply Solutions Roche - Hygromycin B; from Streptomyces hygroscopicus; pkg of 20mL (1 g)
Roche - Hygromycin B; from Streptomyces hygroscopicus; pkg of 20mL (1 g)
eMolecules Medchem Express / Amorolfine (hydrochloride) / 100mg / 446272332 / HY-B0238 / / 78613-38-4 / MFCD00903738 / 353.980 / C21H36ClNO
Medchem Express / Amorolfine (hydrochloride) / 100mg / 446272332 / HY-B0238 / / 78613-38-4 / MFCD00903738 / 353.980 / C21H36ClNO
Medchemexpress LLC IRAK4-IN-4 100mg | 1850276-58-2 | 100 MG
IRAK4-IN-4 is a small-molecule research inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with low-nanomolar potency. It is supplied as a light yellow solid, with molecular formula C22H16N2O2, molecular weight 340.37 g/mol, and high analytical purity. Solubility and storage guidance are provided for in vitro and in vivo use.
- Low-nanomolar IRAK4 potency (IC50 2.8 nM).
- Also inhibits cGAS (IC50 2.1 nM).
- High purity (99.55%).
- Soluble in DMSO (25 mg/mL); in vivo formulation protocols provided.
- Light yellow solid with recommended storage conditions for powder and solutions.